Cotton is soft,good mositure absorbence.Microfiber has a smooth and slippery feel, similar to silk or satin.Microfiber tends to trap more heat.Microfiber is much less absorbent,leaving the moisture to move along the surface until it evaporates. However, if sweat and such gets trapped under a sleeper’s body, then this can create an uncomfortable puddle.
Cotton sheets with high thread counts generally last much longer than cotton sheets with lower thread counts.
Microfiber sheets with a flat weave can use long time. They can withstand frequent washes without deteriorating or pilling. Flat weaves are also less likely to wrinkle or shrink when washed and dried.
Cotton sheets and microfiber sheets both can wash easily,machine wash is ok.
Microfiber sheets and cotton sheets are both available in a wide range of price points, with affordable and luxurious variations. But microfiber sheet sets are cheaper on average than cotton sheets,since they are synthetic.